Frogen® R-404A (HFC-404A) is a non-ozone depleting compound designed to serve as a long-term alternative to Frogen® R-502 (CFC-502) and Frogen® R-22 (HCFC-22) in low and medium temperature commercial refrigeration applications. Applications where Frogen® R-404A is a suitable retrofit refrigerant include supermarket freezer cases, reach-in coolers, display case, transport refrigeration and ice machines.